A number of different conditions can cause neuropathic pain. Not everyone who suffers from these conditions will experience neuropathic pain. The list below shows some of the most common causes, based on whether the damaged nerves are located in the peripheral or central nervous system:
| Causes of peripheral neuropathic pain | Causes of central neuropathic pain |
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| The pain you experience may be the result of touch, changes in temperature, or when you move a part of your body. | The type of pain that you experience with central neuropathic pain can vary greatly. Also, central neuropathic pain may or may not appear immediately, depending on the type of condition that caused it. |